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Presenilin/γ-Secretase and Inflammation
Presenilins (PS) are the catalytic components of γ-secretase, an aspartyl protease that regulates through proteolytic processing the function of multiple signaling proteins. Specially relevant is the γ-secretase-dependent cleavage of the β-amyloid precursor protein (APP) since generates the β-amyloi...
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| Formato: | Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887037/ https://www.ncbi.nlm.nih.gov/pubmed/20559464 http://dx.doi.org/10.3389/fnagi.2010.00016 |