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Presenilin/γ-Secretase and Inflammation

Presenilins (PS) are the catalytic components of γ-secretase, an aspartyl protease that regulates through proteolytic processing the function of multiple signaling proteins. Specially relevant is the γ-secretase-dependent cleavage of the β-amyloid precursor protein (APP) since generates the β-amyloi...

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Detalles Bibliográficos
Autor principal:	Saura, Carlos A.
Formato:	Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2010
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887037/ https://www.ncbi.nlm.nih.gov/pubmed/20559464 http://dx.doi.org/10.3389/fnagi.2010.00016

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