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Novel genes for QTc interval. How much heritability is explained, and how much is left to find?
The corrected QT (QTc) interval is a complex quantitative trait, believed to be influenced by several genetic and environmental factors. It is a strong prognostic indicator of cardiovascular mortality in patients with and without cardiac disease. More than 700 mutations have been described in 12 gen...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887079/ https://www.ncbi.nlm.nih.gov/pubmed/20519034 http://dx.doi.org/10.1186/gm156 |