Inhaled activated protein C protects mice from ventilator-induced lung injury

INTRODUCTION: Activated Protein C (APC), an endogenous anticoagulant, improves tissue microperfusion and endothelial cell survival in systemic inflammatory states such as sepsis, but intravenous administration may cause severe bleeding. We have thus addressed the role of APC delivered locally by inh...

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Detalles Bibliográficos
Autores principales: Maniatis, Nikolaos A, Letsiou, Eleftheria, Orfanos, Stylianos E, Kardara, Matina, Dimopoulou, Ioanna, Nakos, Georgios, Lekka, Marilena E, Roussos, Charalambos, Armaganidis, Apostolos, Kotanidou, Anastasia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887192/
https://www.ncbi.nlm.nih.gov/pubmed/20403177
http://dx.doi.org/10.1186/cc8976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887192/
https://www.ncbi.nlm.nih.gov/pubmed/20403177
http://dx.doi.org/10.1186/cc8976

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