Delta inflation: a bias in the design of randomized controlled trials in critical care medicine

INTRODUCTION: Mortality is the most widely accepted outcome measure in randomized controlled trials of therapies for critically ill adults, but most of these trials fail to show a statistically significant mortality benefit. The reasons for this are unknown. METHODS: We searched five high impact jou...

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Detalles Bibliográficos
Autores principales: Aberegg, Scott K, Richards, D Roxanne, O'Brien, James M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887200/
https://www.ncbi.nlm.nih.gov/pubmed/20429873
http://dx.doi.org/10.1186/cc8990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887200/
https://www.ncbi.nlm.nih.gov/pubmed/20429873
http://dx.doi.org/10.1186/cc8990

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