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Delta inflation: a bias in the design of randomized controlled trials in critical care medicine
INTRODUCTION: Mortality is the most widely accepted outcome measure in randomized controlled trials of therapies for critically ill adults, but most of these trials fail to show a statistically significant mortality benefit. The reasons for this are unknown. METHODS: We searched five high impact jou...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887200/ https://www.ncbi.nlm.nih.gov/pubmed/20429873 http://dx.doi.org/10.1186/cc8990 |