Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure

The central melanocortin system plays a key role in the regulation of food intake and energy homeostasis. We investigated whether genetic or pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in mice and rats with heart failure. Permanent ligation of the left corona...

Descripción completa

Detalles Bibliográficos
Autores principales: Scarlett, Jarrad M, Bowe, Darren D, Zhu, Xinxia, Batra, Ayesha K, Grant, Wilmon F, Marks, Daniel L
Formato: Texto
Lenguaje:English
Publicado: BioScientifica 2010
Materias:
Regular papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887273/
https://www.ncbi.nlm.nih.gov/pubmed/20371568
http://dx.doi.org/10.1677/JOE-09-0397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887273/
https://www.ncbi.nlm.nih.gov/pubmed/20371568
http://dx.doi.org/10.1677/JOE-09-0397

Ejemplares similares