Variability in the Incidence of miRNAs and Genes in Fragile Sites and the Role of Repeats and CpG Islands in the Distribution of Genetic Material

BACKGROUND: Chromosomal fragile sites are heritable specific loci especially prone to breakage. Some of them are associated with human genetic disorders and several studies have demonstrated their importance in genome instability in cancer. MicroRNAs (miRNAs) are small non-coding RNAs responsible of...

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Detalles Bibliográficos
Autores principales: Laganà, Alessandro, Russo, Francesco, Sismeiro, Catarina, Giugno, Rosalba, Pulvirenti, Alfredo, Ferro, Alfredo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887363/
https://www.ncbi.nlm.nih.gov/pubmed/20567512
http://dx.doi.org/10.1371/journal.pone.0011166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887363/
https://www.ncbi.nlm.nih.gov/pubmed/20567512
http://dx.doi.org/10.1371/journal.pone.0011166

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