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New World Hantaviruses Activate IFNλ Production in Type I IFN-Deficient Vero E6 Cells

BACKGROUND: Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS). These viruses induce a strong interferon-stimulated gene (ISG) response in human endothelial cells. African green monkey-derived Vero E6 cells are used to propagate hantavirus...

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Detalles Bibliográficos
Autores principales: Prescott, Joseph, Hall, Pamela, Acuna-Retamar, Mariana, Ye, Chunyan, Wathelet, Marc G., Ebihara, Hideki, Feldmann, Heinz, Hjelle, Brian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887373/
https://www.ncbi.nlm.nih.gov/pubmed/20567522
http://dx.doi.org/10.1371/journal.pone.0011159