Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements

BACKGROUND: The t(9;22)(q34;q11), generating the Philadelphia (Ph) chromosome, is found in more than 90% of patients with chronic myeloid leukemia (CML). As a result of the translocation, the 3' portion of the ABL1 oncogene is transposed from 9q34 to the 5' portion of the BCR gene on chrom...

Descripción completa

Detalles Bibliográficos
Autores principales: Albano, Francesco, Anelli, Luisa, Zagaria, Antonella, Coccaro, Nicoletta, Casieri, Paola, Rossi, Antonella Russo, Vicari, Laura, Liso, Vincenzo, Rocchi, Mariano, Specchia, Giorgina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887383/
https://www.ncbi.nlm.nih.gov/pubmed/20500819
http://dx.doi.org/10.1186/1476-4598-9-120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887383/
https://www.ncbi.nlm.nih.gov/pubmed/20500819
http://dx.doi.org/10.1186/1476-4598-9-120

Ejemplares similares