Non random distribution of genomic features in breakpoint regions involved in chronic myeloid leukemia cases with variant t(9;22) or additional chromosomal rearrangements

BACKGROUND: The t(9;22)(q34;q11), generating the Philadelphia (Ph) chromosome, is found in more than 90% of patients with chronic myeloid leukemia (CML). As a result of the translocation, the 3' portion of the ABL1 oncogene is transposed from 9q34 to the 5' portion of the BCR gene on chrom...

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Detalles Bibliográficos
Autores principales: Albano, Francesco, Anelli, Luisa, Zagaria, Antonella, Coccaro, Nicoletta, Casieri, Paola, Rossi, Antonella Russo, Vicari, Laura, Liso, Vincenzo, Rocchi, Mariano, Specchia, Giorgina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887383/
https://www.ncbi.nlm.nih.gov/pubmed/20500819
http://dx.doi.org/10.1186/1476-4598-9-120

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