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Prediction of CpG-island function: CpG clustering vs. sliding-window methods
BACKGROUND: Unmethylated stretches of CpG dinucleotides (CpG islands) are an outstanding property of mammal genomes. Conventionally, these regions are detected by sliding window approaches using %G + C, CpG observed/expected ratio and length thresholds as main parameters. Recently, clustering method...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887419/ https://www.ncbi.nlm.nih.gov/pubmed/20500903 http://dx.doi.org/10.1186/1471-2164-11-327 |