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Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli

BACKGROUND: H(2)O(2 )produced by vaginal lactobacilli is believed to protect against infection, and H(2)O(2)-producing lactobacilli inactivate pathogens in vitro in protein-free salt solution. However, cervicovaginal fluid (CVF) and semen have significant H(2)O(2)-blocking activity. METHODS: We meas...

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Detalles Bibliográficos
Autores principales: O'Hanlon, Deirdre E, Lanier, Blair R, Moench, Thomas R, Cone, Richard A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887447/
https://www.ncbi.nlm.nih.gov/pubmed/20482854
http://dx.doi.org/10.1186/1471-2334-10-120