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On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study

Testing for genetic effects on mean values of a quantitative trait has been a very successful strategy. However, most studies to date have not explored genetic effects on the variance of quantitative traits as a relevant consequence of genetic variation. In this report, we demonstrate that, under pl...

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Detalles Bibliográficos
Autores principales: Paré, Guillaume, Cook, Nancy R., Ridker, Paul M., Chasman, Daniel I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887471/
https://www.ncbi.nlm.nih.gov/pubmed/20585554
http://dx.doi.org/10.1371/journal.pgen.1000981