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On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study
Testing for genetic effects on mean values of a quantitative trait has been a very successful strategy. However, most studies to date have not explored genetic effects on the variance of quantitative traits as a relevant consequence of genetic variation. In this report, we demonstrate that, under pl...
Autores principales: | Paré, Guillaume, Cook, Nancy R., Ridker, Paul M., Chasman, Daniel I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887471/ https://www.ncbi.nlm.nih.gov/pubmed/20585554 http://dx.doi.org/10.1371/journal.pgen.1000981 |
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