The IG-DMR and the MEG3-DMR at Human Chromosome 14q32.2: Hierarchical Interaction and Distinct Functional Properties as Imprinting Control Centers

Human chromosome 14q32.2 harbors the germline-derived primary DLK1-MEG3 intergenic differentially methylated region (IG-DMR) and the postfertilization-derived secondary MEG3-DMR, together with multiple imprinted genes. Although previous studies in cases with microdeletions and epimutations affecting...

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Detalles Bibliográficos
Autores principales: Kagami, Masayo, O'Sullivan, Maureen J., Green, Andrew J., Watabe, Yoshiyuki, Arisaka, Osamu, Masawa, Nobuhide, Matsuoka, Kentarou, Fukami, Maki, Matsubara, Keiko, Kato, Fumiko, Ferguson-Smith, Anne C., Ogata, Tsutomu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887472/
https://www.ncbi.nlm.nih.gov/pubmed/20585555
http://dx.doi.org/10.1371/journal.pgen.1000992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887472/
https://www.ncbi.nlm.nih.gov/pubmed/20585555
http://dx.doi.org/10.1371/journal.pgen.1000992

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