Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model

Using an adenoviral system as a delivery mediator of therapeutic gene, we investigated the therapeutic effects of the use of combined MDR1 shRNA and human NIS (hNIS) radioiodine gene therapy in a mouse colon xenograft model. In vitro uptake of Tc-99m sestamibi was increased approximately two-fold in...

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Detalles Bibliográficos
Autores principales: Ahn, S J, Jeon, Y H, Lee, Y J, Lee, Y L, Lee, S-W, Ahn, B-C, Ha, J-H, Lee, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887652/
https://www.ncbi.nlm.nih.gov/pubmed/20186172
http://dx.doi.org/10.1038/cgt.2010.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887652/
https://www.ncbi.nlm.nih.gov/pubmed/20186172
http://dx.doi.org/10.1038/cgt.2010.3

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