Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets

BACKGROUND: Spartin protein is involved in degradation of epidermal growth factor receptor and turnover of lipid droplets and a lack of expression of this protein is responsible for hereditary spastic paraplegia type 20 (SPG20). Spartin is a multifunctional protein that associates with many cellular...

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Detalles Bibliográficos
Autores principales: Hooper, Christopher, Puttamadappa, Swamy S, Loring, Zak, Shekhtman, Alexander, Bakowska, Joanna C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887783/
https://www.ncbi.nlm.nih.gov/pubmed/20504295
http://dx.doi.org/10.1186/1741-7007-8-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887783/
https://www.ncbi.nlm.nih.gov/pubmed/20504295
http://dx.doi.org/10.1186/1741-7007-8-72

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