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NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations

BACKGROUND: A recent genome-wide association study (GWAS) has identified a single nucleotide polymorphism (SNP) rs11249433 in the 1p11.2 region as a novel genetic risk factor for breast cancer, and this association was stronger in patients with estrogen receptor (ER)(+ )versus ER(- )cancer. RESULTS:...

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Detalles Bibliográficos
Autores principales: Fu, Yi-Ping, Edvardsen, Hege, Kaushiva, Alpana, Arhancet, Juan P, Howe, Tiffany M, Kohaar, Indu, Porter-Gill, Patricia, Shah, Anushi, Landmark-Høyvik, Hege, Fosså, Sophie D, Ambs, Stefan, Naume, Bjørn, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Prokunina-Olsson, Ludmila
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887795/
https://www.ncbi.nlm.nih.gov/pubmed/20482849
http://dx.doi.org/10.1186/1476-4598-9-113