pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking

BACKGROUND: Huntingtin (htt) is a multi-domain protein of 350 kDa that is mutated in Huntington's disease (HD) but whose function is yet to be fully understood. This absence of information is due in part to the difficulty of manipulating large DNA fragments by using conventional molecular cloni...

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Detalles Bibliográficos
Autores principales: Pardo, Raúl, Molina-Calavita, Maria, Poizat, Ghislaine, Keryer, Guy, Humbert, Sandrine, Saudou, Frédéric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887845/
https://www.ncbi.nlm.nih.gov/pubmed/20515468
http://dx.doi.org/10.1186/1756-6606-3-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887845/
https://www.ncbi.nlm.nih.gov/pubmed/20515468
http://dx.doi.org/10.1186/1756-6606-3-17

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