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Small DNA Pieces in C. elegans Are Intermediates of DNA Fragmentation during Apoptosis
While studying small noncoding RNA in C. elegans, we discovered that protocols used for isolation of RNA are contaminated with small DNA pieces. After electrophoresis on a denaturing gel, the DNA fragments appear as a ladder of bands, ∼10 nucleotides apart, mimicking the pattern of nuclease digestio...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887891/ https://www.ncbi.nlm.nih.gov/pubmed/20585459 http://dx.doi.org/10.1371/journal.pone.0011217 |