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Neutralization of X4- and R5-tropic HIV-1 NL4-3 variants by HOCl-modified serum albumins

BACKGROUND: Myeloperoxidase (MPO), an important element of the microbicidal activity of neutrophils, generates hypochlorous acid (HOCl) from H(2)O(2 )and chloride, which is released into body fluids. Besides its direct microbicidal activity, HOCl can react with amino acid residues and HOCl-modified...

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Detalles Bibliográficos
Autores principales: Polzer, Svenja, van Yperen, Melanie, Kirst, Martin, Schwalbe, Birco, Schaal, Heiner, Schreiber, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887905/
https://www.ncbi.nlm.nih.gov/pubmed/20525179
http://dx.doi.org/10.1186/1756-0500-3-155