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Neutralization of X4- and R5-tropic HIV-1 NL4-3 variants by HOCl-modified serum albumins
BACKGROUND: Myeloperoxidase (MPO), an important element of the microbicidal activity of neutrophils, generates hypochlorous acid (HOCl) from H(2)O(2 )and chloride, which is released into body fluids. Besides its direct microbicidal activity, HOCl can react with amino acid residues and HOCl-modified...
Autores principales: | Polzer, Svenja, van Yperen, Melanie, Kirst, Martin, Schwalbe, Birco, Schaal, Heiner, Schreiber, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887905/ https://www.ncbi.nlm.nih.gov/pubmed/20525179 http://dx.doi.org/10.1186/1756-0500-3-155 |
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