Evaluating oligonucleotide properties for DNA microarray probe design

Most current microarray oligonucleotide probe design strategies are based on probe design factors (PDFs), which include probe hybridization free energy (PHFE), probe minimum folding energy (PMFE), dimer score, hairpin score, homology score and complexity score. The impact of these PDFs on probe perf...

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Detalles Bibliográficos
Autores principales: Xia, Xiao-Qin, Jia, Zhenyu, Porwollik, Steffen, Long, Fred, Hoemme, Claudia, Ye, Kai, Müller-Tidow, Carsten, McClelland, Michael, Wang, Yipeng
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887943/
https://www.ncbi.nlm.nih.gov/pubmed/20236987
http://dx.doi.org/10.1093/nar/gkq039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887943/
https://www.ncbi.nlm.nih.gov/pubmed/20236987
http://dx.doi.org/10.1093/nar/gkq039

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