Cargando…
Photomodulating RNA cleavage using photolabile circular antisense oligodeoxynucleotides
Caged antisense oligodeoxynucleotides (asODNs) are synthesized by linking two ends of linear oligodeoxynucleotides using a photocleavable linker. Two of them (H30 and H40) have hairpin-like structures which show a large difference in thermal stability (ΔT(m) = 17.5°C and 11.6°C) comparing to uncaged...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887953/ https://www.ncbi.nlm.nih.gov/pubmed/20164090 http://dx.doi.org/10.1093/nar/gkq079 |