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Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine

DNA cytosine-5 methylation is a well-studied epigenetic pathway implicated in gene expression control and disease pathogenesis. Different technologies have been developed to examine the distribution of 5-methylcytosine (5mC) in specific sequences of the genome. Recently, substantial amounts of 5-hyd...

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Detalles Bibliográficos
Autores principales: Jin, Seung-Gi, Kadam, Swati, Pfeifer, Gerd P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887978/
https://www.ncbi.nlm.nih.gov/pubmed/20371518
http://dx.doi.org/10.1093/nar/gkq223