Ubiquitin-dependent DNA damage bypass is separable from genome replication

Postreplication repair (PRR) is a pathway that allows cells to bypass or overcome lesions during DNA replication1. In eukaryotes, damage bypass is activated by ubiquitylation of the replication clamp PCNA through components of the RAD6 pathway2. Whereas monoubiquitylation of PCNA allows mutagenic tr...

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Detalles Bibliográficos
Autores principales: Daigaku, Yasukazu, Davies, Adelina A., Ulrich, Helle D.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888004/
https://www.ncbi.nlm.nih.gov/pubmed/20453836
http://dx.doi.org/10.1038/nature09097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888004/
https://www.ncbi.nlm.nih.gov/pubmed/20453836
http://dx.doi.org/10.1038/nature09097

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