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Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement

INTRODUCTION: Urokinase-type plasminogen activator (u-PA) has been implicated in fibrinolysis, cell migration, latent cytokine activation, cell activation, T-cell activation, and tissue remodeling, all of which are involved in the development of rheumatoid arthritis. Previously, u-PA has been report...

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Detalles Bibliográficos
Autores principales: Cook, Andrew D, De Nardo, Christine M, Braine, Emma L, Turner, Amanda L, Vlahos, Ross, Way, Kerrie J, Beckman, S Kaye, Lenzo, Jason C, Hamilton, John A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888184/
https://www.ncbi.nlm.nih.gov/pubmed/20196869
http://dx.doi.org/10.1186/ar2946