Transforming Growth Factor β Promotes Complexes between Smad Proteins and the CCCTC-binding Factor on the H19 Imprinting Control Region Chromatin

Whether signal transduction pathways regulate epigenetic states in response to environmental cues remains poorly understood. We demonstrate here that Smad3, signaling downstream of transforming growth factor β, interacts with the zinc finger domain of CCCTC-binding factor (CTCF), a nuclear protein k...

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Detalles Bibliográficos
Autores principales: Bergström, Rosita, Savary, Katia, Morén, Anita, Guibert, Sylvain, Heldin, Carl-Henrik, Ohlsson, Rolf, Moustakas, Aristidis
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888383/
https://www.ncbi.nlm.nih.gov/pubmed/20427289
http://dx.doi.org/10.1074/jbc.M109.088385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888383/
https://www.ncbi.nlm.nih.gov/pubmed/20427289
http://dx.doi.org/10.1074/jbc.M109.088385

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