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Stromal Hyaluronan Interaction with Epithelial CD44 Variants Promotes Prostate Cancer Invasiveness by Augmenting Expression and Function of Hepatocyte Growth Factor and Androgen Receptor

The main aim of our study is to determine the significance of the stromal microenvironment in the malignant behavior of prostate cancer. The stroma-derived growth factors/cytokines and hyaluronan act in autocrine/paracrine ways with their receptors, including receptor-tyrosine kinases and CD44 varia...

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Detalles Bibliográficos
Autores principales: Ghatak, Shibnath, Hascall, Vincent C., Markwald, Roger R., Misra, Suniti
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888393/
https://www.ncbi.nlm.nih.gov/pubmed/20200161
http://dx.doi.org/10.1074/jbc.M110.104273