Cargando…

Protein Kinase Cθ Negatively Regulates Store-independent Ca(2+) Entry and Phosphatidylserine Exposure Downstream of Glycoprotein VI in Platelets

Platelet activation must be tightly controlled to provide an effective, but not excessive, response to vascular injury. Cytosolic calcium is a critical regulator of platelet function, including granule secretion, integrin activation, and phosphatidylserine (PS) exposure. Here we report that the nove...

Descripción completa

Detalles Bibliográficos
Autores principales: Harper, Matthew T., Poole, Alastair W.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888397/
https://www.ncbi.nlm.nih.gov/pubmed/20388711
http://dx.doi.org/10.1074/jbc.M109.085654