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Protein Kinase Cθ Negatively Regulates Store-independent Ca(2+) Entry and Phosphatidylserine Exposure Downstream of Glycoprotein VI in Platelets
Platelet activation must be tightly controlled to provide an effective, but not excessive, response to vascular injury. Cytosolic calcium is a critical regulator of platelet function, including granule secretion, integrin activation, and phosphatidylserine (PS) exposure. Here we report that the nove...
Autores principales: | Harper, Matthew T., Poole, Alastair W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888397/ https://www.ncbi.nlm.nih.gov/pubmed/20388711 http://dx.doi.org/10.1074/jbc.M109.085654 |
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