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Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages. To investigate the relative contribution of free fatty acids (FFAs) in this process, we de...

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Detalles Bibliográficos
Autores principales: Chandak, Prakash G., Radović, Branislav, Aflaki, Elma, Kolb, Dagmar, Buchebner, Marlene, Fröhlich, Eleonore, Magnes, Christoph, Sinner, Frank, Haemmerle, Guenter, Zechner, Rudolf, Tabas, Ira, Levak-Frank, Sanja, Kratky, Dagmar
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888432/
https://www.ncbi.nlm.nih.gov/pubmed/20424161
http://dx.doi.org/10.1074/jbc.M110.107854