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Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages. To investigate the relative contribution of free fatty acids (FFAs) in this process, we de...
Autores principales: | Chandak, Prakash G., Radović, Branislav, Aflaki, Elma, Kolb, Dagmar, Buchebner, Marlene, Fröhlich, Eleonore, Magnes, Christoph, Sinner, Frank, Haemmerle, Guenter, Zechner, Rudolf, Tabas, Ira, Levak-Frank, Sanja, Kratky, Dagmar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888432/ https://www.ncbi.nlm.nih.gov/pubmed/20424161 http://dx.doi.org/10.1074/jbc.M110.107854 |
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