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Structural Properties of HIV Integrase·Lens Epithelium-derived Growth Factor Oligomers

Integrase (IN) is the catalytic component of the preintegration complex, a large nucleoprotein assembly critical for the integration of the retroviral genome into a host chromosome. Although partial crystal structures of human immunodeficiency virus IN alone and its complex with the integrase bindin...

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Detalles Bibliográficos
Autores principales: Gupta, Kushol, Diamond, Tracy, Hwang, Young, Bushman, Frederic, Van Duyne, Gregory D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888443/
https://www.ncbi.nlm.nih.gov/pubmed/20406807
http://dx.doi.org/10.1074/jbc.M110.114413