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T-cell receptor early signalling complex activation in response to interferon-α receptor stimulation

Signalling through the IFNαR (interferon-α receptor) and TCR (T-cell receptor) in Jurkat T lymphocytes results in distinct immune responses. Despite this both receptors elicit ERK (extracellular-signal-regulated kinase)/MAPK (mitogen-activated protein kinase) phosphorylation. Vav and Slp76 are shown...

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Detalles Bibliográficos
Autores principales: Stevens, Claire N., Simeone, Ann-Marie, John, Susan, Ahmed, Zamal, Lucherini, Orso M., Baldari, C. Tatiana, Ladbury, John E.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888567/
https://www.ncbi.nlm.nih.gov/pubmed/20388118
http://dx.doi.org/10.1042/BJ20091660