MicroRNA 128a Increases Intracellular ROS Level by Targeting Bmi-1 and Inhibits Medulloblastoma Cancer Cell Growth by Promoting Senescence

BACKGROUND: MicroRNAs (miRNAs) are a class of short non-coding RNAs that regulate cell homeostasis by inhibiting translation or degrading mRNA of target genes, and thereby can act as tumor suppressor genes or oncogenes. The role of microRNAs in medulloblastoma has only recently been addressed. We hy...

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Detalles Bibliográficos
Autores principales: Venkataraman, Sujatha, Alimova, Irina, Fan, Rong, Harris, Peter, Foreman, Nicholas, Vibhakar, Rajeev
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888574/
https://www.ncbi.nlm.nih.gov/pubmed/20574517
http://dx.doi.org/10.1371/journal.pone.0010748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888574/
https://www.ncbi.nlm.nih.gov/pubmed/20574517
http://dx.doi.org/10.1371/journal.pone.0010748

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