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Linear and Branched Glyco-Lipopeptide Vaccines Follow Distinct Cross-Presentation Pathways and Generate Different Magnitudes of Antitumor Immunity

BACKGROUND: Glyco-lipopeptides, a form of lipid-tailed glyco-peptide, are currently under intense investigation as B- and T-cell based vaccine immunotherapy for many cancers. However, the cellular and molecular mechanisms of glyco-lipopeptides (GLPs) immunogenicity and the position of the lipid moie...

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Detalles Bibliográficos
Autores principales: Renaudet, Olivier, Dasgupta, Gargi, Bettahi, Ilham, Shi, Alda, Nesburn, Anthony B., Dumy, Pascal, BenMohamed, Lbachir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888579/
https://www.ncbi.nlm.nih.gov/pubmed/20574522
http://dx.doi.org/10.1371/journal.pone.0011216