Elastic network model of allosteric regulation in protein kinase PDK1

BACKGROUND: Structural switches upon binding of phosphorylated moieties underpin many signalling networks. The ligand activation is a form of allosteric modulation of the protein, where the binding site is remote from the structural change in the protein. Recently this structural switch has been ele...

Descripción completa

Detalles Bibliográficos
Autor principal: Williams, Gareth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888814/
https://www.ncbi.nlm.nih.gov/pubmed/20500829
http://dx.doi.org/10.1186/1472-6807-10-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888814/
https://www.ncbi.nlm.nih.gov/pubmed/20500829
http://dx.doi.org/10.1186/1472-6807-10-11

Ejemplares similares