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Assessing circadian rhythms in propofol PK and PD during prolonged infusion in ICU patients
This study evaluates possible circadian rhythms during prolonged propofol infusion in patients in the intensive care unit. Eleven patients were sedated with a constant propofol infusion. The blood samples for the propofol assay were collected every hour during the second day, the third day, and afte...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889282/ https://www.ncbi.nlm.nih.gov/pubmed/20544262 http://dx.doi.org/10.1007/s10928-010-9161-5 |