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Role of KLF15 in Regulation of Hepatic Gluconeogenesis and Metformin Action

OBJECTIVE: An increase in the rate of gluconeogenesis is largely responsible for the hyperglycemia in individuals with type 2 diabetes, with the antidiabetes action of metformin being thought to be achieved at least in part through suppression of gluconeogenesis. RESEARCH DESIGN AND METHODS: We inve...

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Detalles Bibliográficos
Autores principales: Takashima, Mototsugu, Ogawa, Wataru, Hayashi, Kumiko, Inoue, Hiroshi, Kinoshita, Shinichi, Okamoto, Yasuo, Sakaue, Hiroshi, Wataoka, Yu, Emi, Aki, Senga, Yoko, Matsuki, Yasushi, Watanabe, Eijiro, Hiramatsu, Ryuji, Kasuga, Masato
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889759/
https://www.ncbi.nlm.nih.gov/pubmed/20393151
http://dx.doi.org/10.2337/db09-1679