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Role of KLF15 in Regulation of Hepatic Gluconeogenesis and Metformin Action
OBJECTIVE: An increase in the rate of gluconeogenesis is largely responsible for the hyperglycemia in individuals with type 2 diabetes, with the antidiabetes action of metformin being thought to be achieved at least in part through suppression of gluconeogenesis. RESEARCH DESIGN AND METHODS: We inve...
Autores principales: | Takashima, Mototsugu, Ogawa, Wataru, Hayashi, Kumiko, Inoue, Hiroshi, Kinoshita, Shinichi, Okamoto, Yasuo, Sakaue, Hiroshi, Wataoka, Yu, Emi, Aki, Senga, Yoko, Matsuki, Yasushi, Watanabe, Eijiro, Hiramatsu, Ryuji, Kasuga, Masato |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889759/ https://www.ncbi.nlm.nih.gov/pubmed/20393151 http://dx.doi.org/10.2337/db09-1679 |
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