Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes

OBJECTIVE: Depletion of body fat stores during uncontrolled, insulin-deficient diabetes (uDM) results in markedly reduced plasma leptin levels. This study investigated the role of leptin deficiency in the genesis of severe insulin resistance and related metabolic and neuroendocrine derangements indu...

Descripción completa

Detalles Bibliográficos
Autores principales: German, Jonathan P., Wisse, Brent E., Thaler, Joshua P., Oh-I, Shinsuke, Sarruf, David A., Ogimoto, Kayoko, Kaiyala, Karl J., Fischer, Jonathan D., Matsen, Miles E., Taborsky, Gerald J., Schwartz, Michael W., Morton, Gregory J.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889761/
https://www.ncbi.nlm.nih.gov/pubmed/20424233
http://dx.doi.org/10.2337/db09-1918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889761/
https://www.ncbi.nlm.nih.gov/pubmed/20424233
http://dx.doi.org/10.2337/db09-1918

Ejemplares similares