Quantification and Three-Dimensional Imaging of the Insulitis-Induced Destruction of β-Cells in Murine Type 1 Diabetes

OBJECTIVE: The aim of this study was to refine the information regarding the quantitative and spatial dynamics of infiltrating lymphocytes and remaining β-cell volume during the progression of type 1 diabetes in the nonobese diabetic (NOD) mouse model of the disease. RESEARCH DESIGN AND METHODS: Usi...

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Detalles Bibliográficos
Autores principales: Alanentalo, Tomas, Hörnblad, Andreas, Mayans, Sofia, Karin Nilsson, Anna, Sharpe, James, Larefalk, Åsa, Ahlgren, Ulf, Holmberg, Dan
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889776/
https://www.ncbi.nlm.nih.gov/pubmed/20393145
http://dx.doi.org/10.2337/db09-1400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889776/
https://www.ncbi.nlm.nih.gov/pubmed/20393145
http://dx.doi.org/10.2337/db09-1400

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