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Quantification and Three-Dimensional Imaging of the Insulitis-Induced Destruction of β-Cells in Murine Type 1 Diabetes

OBJECTIVE: The aim of this study was to refine the information regarding the quantitative and spatial dynamics of infiltrating lymphocytes and remaining β-cell volume during the progression of type 1 diabetes in the nonobese diabetic (NOD) mouse model of the disease. RESEARCH DESIGN AND METHODS: Usi...

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Detalles Bibliográficos
Autores principales:	Alanentalo, Tomas, Hörnblad, Andreas, Mayans, Sofia, Karin Nilsson, Anna, Sharpe, James, Larefalk, Åsa, Ahlgren, Ulf, Holmberg, Dan
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889776/ https://www.ncbi.nlm.nih.gov/pubmed/20393145 http://dx.doi.org/10.2337/db09-1400

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