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The Glucagonostatic and Insulinotropic Effects of Glucagon-Like Peptide 1 Contribute Equally to Its Glucose-Lowering Action

OBJECTIVE: Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell function, while the inhibition of α-cell secretion has received less attention. The aim of this research was to quan...

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Detalles Bibliográficos
Autores principales: Hare, Kristine J., Vilsbøll, Tina, Asmar, Meena, Deacon, Carolyn F., Knop, Filip K., Holst, Jens J.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889777/
https://www.ncbi.nlm.nih.gov/pubmed/20150286
http://dx.doi.org/10.2337/db09-1414