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E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor-β

OBJECTIVE: Increased deposition of extracellular matrix (ECM) within the kidney is driven by profibrotic mediators including transforming growth factor-β (TGF-β) and connective tissue growth factor (CTGF). We investigated whether some of their effects may be mediated through changes in expression of...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Herman-Edelstein, Michal, Koh, Philip, Burns, Wendy, Jandeleit-Dahm, Karin, Watson, Anna, Saleem, Moin, Goodall, Gregory J., Twigg, Stephen M., Cooper, Mark E., Kantharidis, Phillip
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889781/
https://www.ncbi.nlm.nih.gov/pubmed/20393144
http://dx.doi.org/10.2337/db09-1736