Cargando…
E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor-β
OBJECTIVE: Increased deposition of extracellular matrix (ECM) within the kidney is driven by profibrotic mediators including transforming growth factor-β (TGF-β) and connective tissue growth factor (CTGF). We investigated whether some of their effects may be mediated through changes in expression of...
Autores principales: | Wang, Bo, Herman-Edelstein, Michal, Koh, Philip, Burns, Wendy, Jandeleit-Dahm, Karin, Watson, Anna, Saleem, Moin, Goodall, Gregory J., Twigg, Stephen M., Cooper, Mark E., Kantharidis, Phillip |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889781/ https://www.ncbi.nlm.nih.gov/pubmed/20393144 http://dx.doi.org/10.2337/db09-1736 |
Ejemplares similares
-
miR-200a Prevents Renal Fibrogenesis Through Repression of TGF-β2 Expression
por: Wang, Bo, et al.
Publicado: (2011) -
Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor-β: A Model for Diabetic Podocytopathy
por: Herman-Edelstein, Michal, et al.
Publicado: (2011) -
Alagebrium Reduces Glomerular Fibrogenesis and Inflammation Beyond Preventing RAGE Activation in Diabetic Apolipoprotein E Knockout Mice
por: Watson, Anna M.D., et al.
Publicado: (2012) -
Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse
por: Chew, Phyllis, et al.
Publicado: (2010) -
Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes
por: Soro-Paavonen, Aino, et al.
Publicado: (2008)