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Increased Expression of β-N-Acetylglucosaminidase in Erythrocytes From Individuals With Pre-diabetes and Diabetes

OBJECTIVE: O-linked β-N-acetylglucosamine (O-GlcNAc) plays an important role in the development of insulin resistance and glucose toxicity. O-GlcNAcylation is regulated by O-GlcNAc transferase (OGT), which attaches O-GlcNAc to serine and/or threonine residues of proteins and by O-GlcNAcase, which re...

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Detalles Bibliográficos
Autores principales: Park, Kyoungsook, Saudek, Christopher D., Hart, Gerald W.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889787/
https://www.ncbi.nlm.nih.gov/pubmed/20413512
http://dx.doi.org/10.2337/db09-1086