Targeting Mitochondrial Cell Death Pathway to Overcome Drug Resistance with a Newly Developed Iron Chelate

BACKGROUND: Multi drug resistance (MDR) or cross-resistance to multiple classes of chemotherapeutic agents is a major obstacle to successful application of chemotherapy and a basic problem in cancer biology. The multidrug resistance gene, MDR1, and its gene product P-glycoprotein (P-gp) are an impor...

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Detalles Bibliográficos
Autores principales: Ganguly, Avishek, Basu, Soumya, Chakraborty, Paramita, Chatterjee, Shilpak, Sarkar, Avijit, Chatterjee, Mitali, Choudhuri, Soumitra Kumar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889820/
https://www.ncbi.nlm.nih.gov/pubmed/20582168
http://dx.doi.org/10.1371/journal.pone.0011253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889820/
https://www.ncbi.nlm.nih.gov/pubmed/20582168
http://dx.doi.org/10.1371/journal.pone.0011253

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